Surrogacy Protocols

protocolSurrogacy has become popular in the last few years across the world and India has become one of the most popular destinations for this due to various reasons. Relatively cheap medical expenses, availability of world class medical facilities and flexible laws have given a new boom to this activity in India. The process of surrogacy is complicated and has to be carries with maximum care and precautions. Right from selecting appropriate surrogate mother to actual fertilization process, all steps are taken extremely carefully and any small mistake might lead to unsuccessful attempt.

One of the most critical and important step in this process is to match the menstrual cycle of the genetic mother and the surrogate mother in case of IVF surrogacy. Since two females are involved in this, the ovulation period and hormonal levels have to be synchronized to make the fertilization possible. There are mainly two types of protocols are used in case of IVF surrogacy in India. The method used to match the cycle is oral contraceptive pills. The calculated prescription of these pills regulates the cycle and the surrogacy process can be done. There are various factors like age of the genetic mother and the results of various medical tests that are carried out for the genetic mother helps in deciding the suitable protocol for that particular pregnancy.

Protocol - Day 2 : this protocol is known as antagon protocol also in the medical terminology. The oral contraceptive pills are started in the previous month. On the second day of the menstruation-flow, a special drug is injected that is called gondatropin. Daily the USG is monitored and after the follicle size reaches up to 14mm, there is a drug called as antagon is injected in the genetic mother’s body. This drug prevents the flow of endogenous hormones.

Protocol - Day 21: This protocol is known as long protocol also in the medical terminology. In this case, a special drug called as GnRH analogue is given from the 21st day of the previous menstrual cycle of the genetic mother. The drug known as gondatropin is given to her as soon as the menstrual-flow starts. After the follicle sizes reaches to 18mm. HCG trigger is given to her through injection. The surrogate mother is given progesterone hormone tablet from the same day. The egg is taken after 36 hours of this that comes generally on the 12th or 13th day of the menstrual cycle. The egg is inseminated with the sperm taken from the father on the same day in the laboratory.

The embryo is then planted in the womb of the surrogate mother. There are progesterone tablets or injections are given to the surrogate mother for few more days. The final confirmation of the pregnancy comes after 15 days. Surrogate mothers are always kept under strict medical supervision and care since this pregnancy is always considered high risk pregnancy and any small negligence or carelessness might lead to not only unsuccessful pregnancy, but it can be fatal for the surrogate mother as well.